Our Team

Principal Investigator

Brad Hoffman

Dr. Hoffman is an Associate Professor and cellular immunologist with a major interest in immune modulation and tolerance induction using adeno-associated virus (AAV) gene therapy. Dr. Hoffman earned his Ph.D. in Immunology from Temple University School of Medicine in 2006. He subsequently performed postdoctoral research in gene therapy at University of Florida.

In 2010, he received the Kokomoor Award for Excellence in Pediatric Research and became an Assistant Professor of Pediatrics in the Division of Cellular & Molecular Therapy.

Dr. Hoffman’s research has earned him multiple awards and grants, including an American Heart Association Fellowship (2007), Pfizer Award in Hemophilia Research (ASPIRE, 2011), BD Bioscience Immunology Award (2011), Children’s Miracle Network grant (2012-13), National Multiple Sclerosis Society Pilot grant (2014), and research grant (2015). He is also a NIH – Pediatric Research LRP Recipient (2012-14).

Most recently (Dec. 2018), Dr. Hoffman received the Scientific Researcher Award from the National Multiple Sclerosis Society.


Geoffrey D Keeler
Department: MD-PEDS-CELL / MOLEC THERP DIV

Geoffrey D Keeler

Research Assistant Professor
Isabelle Cote
Department: MD-PEDS-CELL / MOLEC THERP DIV

Isabelle Cote

Assistant Scientist
Cristina D Gaddie
Department: MD-PEDS-CELL / MOLEC THERP DIV

Cristina D Gaddie

Biological Scientist III
Addelynn S Sagadevan
Department: MD-PEDS-CELL / MOLEC THERP DIV

Addelynn S Sagadevan

GRADUATE AST-R
David M Mahan
Department: HO-GRAHAM / HUME AREA

David M Mahan

HS – RESIDENCE ASSISTANT

Undergraduate Students

  • David Mahan
  • Duncan Lewis

Previous Members

  • Emily Silverberg
  • Noah Jones